None listed
Conditions
Interventions
Intervention1: Arm 1: Multi-faceted complex intervention starting pre-conceptionally and continuing through pregnancy and post-natally.: The multi-faceted interventions comprise: a) measures to optimi
b) a group parenting programme integrated with cognitive behavior therapy
c) a lifestyle behavior change intervention to support women to achieve a diverse diet, exclusive breastfeeding for the first 6 months, timely introduction of diverse and nutritious infant weaning foo
and d) the reduction of environmental pollution focusing on indoor air pollution and toxin avoidance.
Intervention2: Arm 2: Multi-faceted complex intervention starting in pregnancy and continuing thro
and d) the reduction of environmental pollution focusing on indoor air pollution and toxin avoidance.
Control Intervention1: Arm 3: Enhanced standard of care.: This group will receive an enhanced stan
Sponsors
CSI Holdsworth Memorial Hospital
Vivekananda Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Married women over the age of 18 years with no children or one child and intend to have a child within the next two years.
Exclusion criteria
Exclusion criteria: Women with two or more children.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome at age 5 years in the children (across all HeLTI cohorts) is adiposity as measured by fat mass index (fat mass/height2), using DXA (dual x-ray absorptiometry).Timepoint: 5 years of age in the child. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other key outcomes at 5 years in the children include: • Overweight and obesity (OWO) as assessed by BMI and indicators of body composition and distribution (waist circumference, skinfold thickness) • Glucose metabolism as measured by fasting venous plasma glucose concentration • Resting systolic blood pressure • Child development as assessed using modified Kaufman battery, validated for Indian settings. Timepoint: 5 years of age. | — |
Countries
India
Contacts
Public ContactKiran KN
Epidemiology Research Unit, CSI Holdsworth Memorial Hospital, Mysore.
Outcome results
None listed