To study the difference between weight bearing immediately 1 day after surgery versus weight bearing 12 weeks after surgery with plate/screw fixation of lower part of knee fractures, which encroach into the knee joint.

To Study the effect of early versus late weight bearing after osteosynthesis of proximal tibia fractures.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/12/030130

Enrollment

Registered

2020-12-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S821- Fracture of upper end of tibia

Interventions

Intervention1: Plate/Screw fixation and non weight bearing.: All the patients planned for osteosynthesis will be randomly allocated into either of the two different rehabilitation protocols. Group II

Eligibility

Inclusion criteria

Inclusion criteria: Closed Intra-articular proximal tibia fractures in skeletally mature patients, requiring osteosynthesis.

Exclusion criteria

Exclusion criteria: 1. Intra-articular fracture not requiring osteosynthesis, 2. Intra-articular eminence fracture, 3. Open fractures, 4. Associated other lower limb fracture, 5. Foot deformities, 6. Limb length discrepancy >2cm, 7. Pathological fracture, 8. Skeletally immature patient, 9 Neurological injury, 10. Vascular injury, 11. Late presentation after >3weeks, 12. Previous surgery of the knee, 13. Previous septic episode, 14. Post-traumatic deformity, 15. Inflammatory arthritis, 16. Pre-existing degenerative Osteoarthritis, 17. Neuromuscular disorder involving either of lower limb.

Design outcomes

Primary

Measure	Time frame
1. To identify difference in gait patterns among patients with early weight bearing protocol and late weight bearing protocol by measuring lower limb symmetry indices after osteosynthesis of proximal tibia fractures. 2. To study the effect of early weight bearing protocol and late weight bearing protocol in patients after osteosynthesis of proximal tibia fracture on synovial fluid biomarkers.Timepoint: Lower limb symmetry indices and synovial fluid biomarkers to be assessed at 6 months postoperatively.	—

Measure

Time frame

1. To identify difference in gait patterns among patients with early weight bearing protocol and late weight bearing protocol by measuring lower limb symmetry indices after osteosynthesis of proximal tibia fractures. 2. To study the effect of early weight bearing protocol and late weight bearing protocol in patients after osteosynthesis of proximal tibia fracture on synovial fluid biomarkers.Timepoint: Lower limb symmetry indices and synovial fluid biomarkers to be assessed at 6 months postoperatively.

—

Secondary

Measure	Time frame
To study the difference between early and late weight bearing protocol after osteosynthesis of proximal tibia fractures on functional and radiological outcome.Timepoint: 15th day, 1st month, 45th day, 2nd month, 3rd month and 6th month postoperatively.	—

Countries

India

Contacts

Public ContactDr Devendra Chouhan

Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh.

drdevnim@gmail.com7087008154

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026