comparative study of use of intraperitoneal drugs ( local anesthetics and adjuvants) for postoperative pain management after laparoscopic surgeries.

comparative study of efficacy of intraperitoneal instillation of 0.2% ropivacaine with dexmedetomidine versus 0.2% ropivacaine with ketamine in laparoscopic surgeries - a randomized study

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/12/030121

Enrollment

105

Registered

2020-12-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K35- Acute appendicitis Health Condition 2: K800- Calculus of gallbladder with acutecholecystitis Health Condition 3: K802- Calculus of gallbladder without cholecystitis Health Condition 4: K811- Chronic cholecystitis Health Condition 5: N832- Other and unspecified ovarian cysts

Interventions

Intervention1: intraperitoneal instillation of local anesthetic with adjuvant: local anesthetic along with adjuvants will be instilled intraperitoneally in laparoscopic surgeries for postoperative pa

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS WITH ASA PS I & II POSTED FOR ELECTIVE LAPAROSCOPIC SURGERIES

Exclusion criteria

Exclusion criteria: Patient refusal Local anesthetic allergy / drug allergy Pregnancy Patients with Cardiovascular/Respiratory/ Liver/ Renal diseases BMI >= 30 Kg/m2 If any other surgeries combined in the same sitting

Design outcomes

Primary

Measure	Time frame
To study the total duration of analgesia and total rescue analgesic dose requirements in first 24 hours post operatively.Timepoint: for every 30 min for first two hours and then at 6 hours,12 hours and 24 hours.	—

Secondary

Measure	Time frame
The hemodynamic parameters intraoperatively and postoperatively. Incidence of postoperative nausea and vomiting using Likert scale. Depth of sedation using Ramsay sedation score. Incidence of shoulder tip pain using VAS. Timepoint: for every 30 min for first two hours and then at 6 hours,12 hours and 24 hours.	—

Countries

India

Contacts

Public ContactDUDYALA DHATRI

KALINGA INSTITUTE OF MEDICAL SCIENCES

amritapanda1323@gmail.com9439862335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026