Comparison of Dexmeditomidine, Fentanyl as an adjuvant to Bupivacaine for Unilateral spinal anaesthesia in lower limb surgery.

Comparison of Bupivacaine-Dexmedetomidine vs Bupivacaine-Fentanyl vs Bupivacaine -Saline for Unilateral spinal anaesthesia in lower limb surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/12/030095

Enrollment

120

Registered

2020-12-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified Health Condition 2: M848- Other disorders of continuity of bone

Interventions

Intervention1: Bupivacaine-Dexmedetomidine: Inj 0.5%Bupivacaine 1ml+Inj Dexmedetomidine 5mcg given intrathecally once before procedure Intervention2: Bupivacaine-Fentanyl: Inj 0.5% Bupivacaine 1ml +I

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for lower limb surgeries of one side

Exclusion criteria

Exclusion criteria: Patient refusal Local site infection Coagulopathy

Design outcomes

Primary

Measure	Time frame
Onset of sensory block, Maximum duration of sensory block, Onset of motor block, Maximum duration of motor block .Timepoint: Onset of sensory block- 1,5,10,15,30,45,60,90,120 minutes Onset of motor block-1,5,10,15,30,60,90,120 minutes Maximum duration of motor block-1,5,10,15,30,60,90,120 minutes.	—

Secondary

Measure	Time frame
Duration of post operative analgesiaTimepoint: Duration of post operative analgesia till 240mins	—

Countries

India

Contacts

Public ContactMAMTA G PATEL

DEPARTMENT OF ANESTHESIOLOGY

mgpatel111@yahoo.com9825453024

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026