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Postoperative Analgesia in patients of Anterior Cervical Discectomy and Fusion (ACDF) Surgery

Comparison of Ketamine Versus Fentanyl Infusion for Postoperative Analgesia in patients undergoing Anterior Cervical Discectomy and Fusion (ACDF)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/030091
Enrollment
82
Registered
2020-12-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection Ketamine for post operative analgesia in ACDF surgery: Drug to be started at 0.25 mg/kg/hr intraoperatively and then continued at 0.125 mg/kg/hr post operatively Control Inter

Sponsors

Dr Tarun Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA physical status I and II, aged 18 to 65 years with of BMI <30 with cervical disc prolapse scheduled for single or multiple level anterior cervical discectomy and fusion.

Exclusion criteria

Exclusion criteria: Patients who have traumatic cervical spine injury, underwent prior cervical disc surgery, prior respiratory compromise, preoperative opioid or steroids use, hypersensitivity to the subject drugs and patients whose mental status will affect the completion of the QoR-15 questionnaire.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of ketamine versus fentanyl infusion for postoperative analgesia in patients undergoing ACDF in terms of: a.Visual Analog Score b. Time to first rescue analgesic c. Number and total dose of rescue analgesicTimepoint: Intraoperative and 24 hours post operative period—

Secondary

MeasureTime frame
To compare: a.Degree of overall satisfaction using quality of recovery score (QoR score). b.Hemodynamic variables between the two groups in intra and postoperative period. c.Incidence of postoperative complications like as nausea, vomiting, hypotension, dry mouth, allergic reaction, respiratory depression, urinary retention and dysphoria. d.Postoperative sedation (Ramsay Sedation Score) Timepoint: Intraoperative and 24 hours post operative period—

Countries

India

Contacts

Public ContactDr Neelesh Bhatnagar

Geetanjali Medical College andHospital

drneelesh1106@gmail.com8890663427

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026