Compare response to vitamin D in obese vs non obese children.

Response to weekly oral doses of vitamin D in vitamin D deficient overweight and obese versus normal BMI children of 5 to 12 years age.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/12/030062

Enrollment

Registered

2020-12-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases

Interventions

Intervention1: Vitamin D: 60000 IU weekly for 5 weeks to overweight and obese children aged 5 - 12 years Control Intervention1: Vitamin D: 60000 IU weekly for 5 weeks to normal BMI children aged 5-12

Eligibility

Inclusion criteria

Inclusion criteria: Obese group- Overweight and obese Indian children ( BMI = 23rd adult equivalent of IAP BMI charts ) of age group 5 to 12 years presenting to Out-patient clinic and pediatric endocrinology clinic at Chacha Nehru Bal Chikitsalaya, Delhi will be screened and included in the study if their serum 25(OH)D levels are less than 20 ng/ml. Normal BMI- Apparently healthy children, ( BMI

Exclusion criteria

Exclusion criteria: 1.Children with confirmed or suspected malabsorption, renal or hepatic disorders. 2.Children who had received vitamin D in therapeutic doses in last 6 months. 3.Children on psoralen and ultraviolet A therapy (PUVA) for some skin disorder. 4.Children who had received drugs that may interfere with vitamin D metabolism like anticonvulsants, steroids, chemotherapy, antitubercular drugs, H2 Blockers, and thiazide diuretics and those on any herbal or ayurvedic medications. 5.Children with any known systemic illness or endocrine or metabolic disorder known to be associated with obesity either before or during the course of study or subjects with symptoms suggestive of hypothalamic obesity.

Design outcomes

Primary

Measure	Time frame
Change in serum 25(OH)D from baseline to 1month post supplementation with weekly ( 60,000 IU for 5 weeks) oral dose of vitamin D in overweight and obese versus normal BMI vitamin D deficient children in age group 5-12 years.Timepoint: Change in serum 25(OH)D from baseline to 1month post supplementation with weekly ( 60,000 IU for 5 weeks) oral dose of vitamin D in overweight and obese versus normal BMI vitamin D deficient children in age group 5-12 years.	—

Measure

Time frame

Change in serum 25(OH)D from baseline to 1month post supplementation with weekly ( 60,000 IU for 5 weeks) oral dose of vitamin D in overweight and obese versus normal BMI vitamin D deficient children in age group 5-12 years.Timepoint: Change in serum 25(OH)D from baseline to 1month post supplementation with weekly ( 60,000 IU for 5 weeks) oral dose of vitamin D in overweight and obese versus normal BMI vitamin D deficient children in age group 5-12 years.

—

Secondary

Measure	Time frame
Change in serum 25(OH)D from baseline to 1month post supplementation with weekly ( 60,000 IU for 5 weeks) oral dose of vitamin D in overweight and obese versus normal BMI vitamin D deficient children in age group 5-12 years.Timepoint: Baseline to 1 month post supplementation	—

Countries

India

Contacts

Public ContactDr Kanhaiya Lal

Chacha Nehru Bal Chikitsalaya

goelmedha@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026