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safety of remdesivir use in patients with impaired kidney function and covid 19 infection

safety of Remdesivir use in patients with acute or chronic kidney disease and covid 19 infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/12/030046
Enrollment
100
Registered
2020-12-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N179- Acute kidney failure, unspecified Health Condition 2: N189- Chronic kidney disease, unspecified Health Condition 3: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

DrMaulin Shah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All covid positive (Rapid antigen test or RT PCR) patients admitted in shree Krishna hospital from March 2020 whose presenting creatinine is more than 1.4 mg/dl in Male or 1.2 mg/dl in Female or who are having oliguria /anuria (urine output less than 0.5 ml/kg/hour in first 24 hours -as per Standard KDIGO criteria) and who also received Remdesivir short or prolonged course during hospital stay will be included.

Exclusion criteria

Exclusion criteria: Those Covid positive patients with renal dysfunction will be excluded from study if they do not complete the course of remdesevir suggested by clinician. However, those patients who expired during treatment of remdesivir will be included in study and they will be analyzed separately.

Design outcomes

Primary

MeasureTime frame
Remdesevir is safe in patients with acute or chronic kidney injury and covid 19 infectionTimepoint: 4 weeks

Secondary

MeasureTime frame
reduction in hospital stay and mortality in chronic kidney disease patients infected with covid 19 infection and severe lung involvement treated with remdesevirTimepoint: 8 weeks

Countries

India

Contacts

Public ContactDrMaulin Shah

Pramukhswami medical college,H M Patel centre for medical care and education

mauls39@gmail.com9904163277

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026