FindTrial
Sign In

Comparison of two drugs in spinal anaesthesia for lower limb orthopaedic surgeries

COMPARISON OF EFFECT OF ADDING INTRATHECAL MgSO4 (50%) TO BUPIVACAINE (0.5%) VERSUS DEXMEDITOMEDINE TO BUPIVACAINE (0.5%) FOR LOWER LIMB ORTHOPAEDIC SURGERIES.â??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/030033
Enrollment
80
Registered
2020-12-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S828- Other fractures of lower leg

Interventions

Control Intervention1: Dexmedetomidine: Comparison of Inj. Dexmedetimidine (dose: 0.1 ml, route: intra thecal) Control Intervention2: Mgso4: inj. Mgso4 (dose: 50mg,0.1 ml, route: intra thecal)

Sponsors

Department of AnaesthesiologyGoverment medical college bhavnagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grades: I, II and III. Participant undergoing lower limb surgery under subarachnoid block. A written informed consent obtained from participant.

Exclusion criteria

Exclusion criteria: Participants having contraindications to subarachnoid block like congenital spinal anomalies, altered coagulation profile, local site skin infection. Participants having severe psychiatric disorders like depression, dementia or any other psychiatric illness and are not compatible for subarachnoid block. - Participants having neurological diseases like brain tumour, CNS syphilis, meningitis. Spinal cord and peripheral nerve diseases, poliomyelitis, multiple sclerosis. Participants with allergy to local anaesthetic drug or study drug. Pregnant lady and lactating mother. Chronic headache. eg.migraine.

Design outcomes

Primary

MeasureTime frame
To compare the onset, peak, duration and regression of sensory and motor blockage in both groups. To compare the onset, peak, duration and regression of motor blockage in both groups. To compare period of postoperative analgesia in both groups. Timepoint: To measure vitals, and semsory and motor block effects at specific time interval. Time 0, after immediately giving spinal anaesthesia, and then at the time point of 1,2,3,5,10,15,30,60,90,120 mins and for post operative analgesia and effect regression 4 hours post operatively.—

Secondary

MeasureTime frame
to compare heamodynemic status of pt, and any side effects.Timepoint: Time 0(immediately after block) and then at 1,2,3,5,10,15,30,60,90,120 mins.—

Countries

India

Contacts

Public ContactDr Meha Pathak

GMC Bhavnagar

drshilpadoshi@yahoo.in9428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026