Effect of sevoflurane on neonates undergoing surgery

Impact of sevoflurane anesthesia on S-Adenosylmethionione in neonates

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/12/030026

Enrollment

Registered

2020-12-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Taking arterial blood to determine levels of S Adenosylmethionione before start of sevoflurane and after cut of sevoflurane under general anesthesia: To know the effect of sevofluran

Eligibility

Inclusion criteria

Inclusion criteria: Neonates undergoing surgery under general anesthesia Haemodynamically stable neonates

Exclusion criteria

Exclusion criteria: Severe sepsis Haemodynamically unstable neonates

Design outcomes

Primary

Measure	Time frame
To evaluate the levels of S-Adenosylmethionione following sevoflurane anesthesia in neonatesTimepoint: Adenosylmethionine levels checked before starting sevoflurane and after cutting sevoflurane under general anesthesia	—

Secondary

Measure	Time frame
To correlate between duration of sevoflurane exposure and S-AdenosylmethionioneTimepoint: Duration of sevoflurane anesthesia is calculated at the end and correlated with SAM levels	—

Countries

India

Contacts

Public ContactSaraswathi Nagapaa

Bangalore medical college and research institute

dr.saraswathi.pmssy@gmail.com09663304834

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026