Skip to content

Difference in diaphragmatic thickness in patients on two type of mechanical ventilation

Comparison of diaphragmatic atrophy in patients on ventilator support with SIMV+PS mode and PRVC mode: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/030022
Enrollment
62
Registered
2020-12-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J969- Respiratory failure, unspecified

Interventions

Intervention1: Mode of mechanical ventilation: Patients will be divided into two groups. One group of patient will be put on SIMV PS mode and another group will be put on PRVC mode of mechanical venti

Sponsors

Postgraduate institute of medical education and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring mechanical ventilation in the Intensive Care Unit

Exclusion criteria

Exclusion criteria: 1.Mechanical ventilation before coming into Intensive Care Unit 2.Patients who are not started on enteral feeding within 24 hours of coming into Intensive Care Unit 3.Patients with neuromuscular disorders and anatomical malformation of the thorax 4.Patients with neuroparalytic snake bite 5.Patients with spinal and brachial plexus injury 6.Patients with organophosphorus poisoning 7.Usage of neuromuscular blockers during mechanical ventilation

Design outcomes

Primary

MeasureTime frame
Diaphragmatic atrophy in terms of diaphragm muscle thicknessTimepoint: One measurement taken within 6 hours of initiation of mechanical ventilation and another measurement done at 72 hours of mechanical ventilation

Secondary

MeasureTime frame
Days of mechanical ventilation Timepoint: At the time of discontinuing the mechanical ventilation for the patient;Days of stay in intensive care unitTimepoint: At the time of discharge of the patient from the intensive care unit;Weaning FailureTimepoint: At the time of starting to wean the patient

Countries

India

Contacts

Public ContactL N Yaddanapudi

Postgraduate institute of medical education and research

narayana.yaddanapudi@gmail.com9815836656

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026