Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
All India Institute of Medical Sciences Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: - Patients tested COVID-19 positive by Reverse Transcriptase Polymerase Chain Reaction (rt-PCR) test and admitted in Corona Critical Care wards at AIIMS, Jodhpur till January 31, 2021 - Requiring the use of High FLow Nasal Oxygen Therapy
Exclusion criteria
Exclusion criteria: - Patients who / whose proxies refuse to consent to use of their data for research - Patients who were on non-invasive / invasive mechanical ventilation before the use of HFNC (High Flow Nasal Cannula)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of patients who did not require intubation and invasive mechanical ventilation by using HFNC as a rescue modality to manage hypoxemia in rt-PCR confirmed Covid-19 patients admitted to the critical care settingTimepoint: At the time of initiating HFNC and daily at 24hrs intervals after till a positive / negative outcome is reached | — |
Secondary
| Measure | Time frame |
|---|---|
| The 28 days all-cause mortality and length of ICU/CCCU stay in these patientsTimepoint: Time of discharge and 28 days post admission;The blood gas parameters (Po2 and PFR) of patients taken on HFNC and their trends over time of useTimepoint: At the time of initiating HFNC and daily at 24hrs intervals after till a positive / negative outcome is reached;The duration of HFNC requiredTimepoint: At the time of initiating HFNC and daily at 24hrs intervals after till a positive / negative outcome is reached;The validity of using ROX and modified ROX indices as a predictor of intubation and hence failure of HFNCTimepoint: 2hrs, 6hrs, 12hrs and subsequently at 24hr intervals post initiating HFNC use;To compare the data among various demographics and patients with varied comorbiditiesTimepoint: At the time of initiating HFNC and daily at 24hrs intervals after till a positive / negative outcome is reached | — |
Countries
India
Contacts
Public ContactDr Samarth Agarwal
All India Institute of Medical Sciences, Jodhpur
Outcome results
None listed