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This study will help us in understanding how this disease progresses and why some became sicker. This study may also help in the development of novel therapy.

Characterization of the proteolytic processes in the serum of patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pneumonia- a pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/12/029983
Enrollment
100
Registered
2020-12-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

Control Intervention1: None: None

Sponsors

National Institute of malaria Research New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult of both sexes sufferings or recovered from covid 19 pneumonia will be recruited

Exclusion criteria

Exclusion criteria: Patients with pre-existing respiratory diseases i.e. active pulmonary tuberculosis, bronchial asthma, and chronic obstructive pulmonary disease will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
â?¢Differential protease expression in patients with SARS-CoV-2 infection who required supplemental oxygen/invasive/non-invasive ventilation vs healthy individuals and mild COVID patients who didnâ??t require supplemental oxygen. â?¢Identification of unusual proteases and their inhibitors. â?¢Identification and database preparation of target proteins involved in the pathogenesis of SARS-CoV-2 disease. Timepoint: At base line—

Secondary

MeasureTime frame
NoneTimepoint: None—

Countries

India

Contacts

Public ContactSajal De

AIIMS, Raipur

sajalde@yahoo.com09406573825

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026