Health Condition 1: G403- Generalized idiopathic epilepsy and epileptic syndromes
Conditions
Interventions
Intervention1: Sevoflurane: In children who have been randomly assigned to receive sevoflurane (Group S), an appropriately sized facemask will be secured in place using a harness. The dial concentrati
Sponsors
Seth GS Medical College and KEM Hospital Mumbai
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiology (ASA) status I and II children between 1-12years of age, without any evidence of an anticipated difficult airway and severe systemic disease.
Exclusion criteria
Exclusion criteria: 1. Severe cardiovascular, pulmonary, endocrine, renal and hepatic disease 2. Severe airway or craniofacial abnormality 3. History of propofol intolerance, family history of malignant hyperthermia and mitochondrial disease, 4. Fat metabolism disorder 5. Imaging for acute trauma 6. History suggestive of recent respiratory tract infection 7. Inadequate fasting 8. Children receiving intravenous anesthetic agents or sedative agents other than propofol 9. Children with tracheostomy in-situ 10. Children requiring mechanical ventilation, supplemental oxygen and inotropic support
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate the efficacy of sevoflurane in comparison to propofol in terms of interruptions in paediatric MRI during maintenance of anaesthesiaTimepoint: On completion of the MRI scan | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the following parameters between the two study groups: (a) Time to awakening (b) Time spent in PACU until fulfillment of PACU discharge criteria (c) Incidence of respiratory complications during the MRI scan (d) Incidence of cardiovascular complications during the MRI scan (e) Incidence of emergence delirium (g) Incidence of post-procedure vomitingTimepoint: All the above mentioned secondary outcomes will be assessed on completion of MRI scan | — |
Countries
India
Contacts
Public ContactAkhil Goel
Seth GS Medical College and KEM Hospital, Mumbai
Outcome results
None listed