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Platelet rich plasma injections in patients of chronic low back pain

Effect of Autologous PRP in atrophied multifidus muscle in patients of chronic low back pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029927
Enrollment
40
Registered
2020-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M545- Low back pain

Interventions

Intervention1: Local Anaesthetic will be injected in patients of low back pain: Lignocaine mixed with antibiotics will be injected in the atrophied multifidus muscle of patients with low back pain Con

Sponsors

Institute of medical sciences BHU Varanasi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.voluntary signature and informed written written consent 2.Axial low back pain for more than 3 months atleast 3.Recent MRI (within last 6 months) consistent kader grade 2 or 3 multifidus atrophy at 1 or 2 levels 4.Is independent,ambulatory and can comply with all postoperative evaluation and visit.

Exclusion criteria

Exclusion criteria: 1.Mild multifidus atrophy kader grade 1 2.Multifidus atrophy at more than 2 levels 3.Symptomatic spinal stenosis(eg pseudoclaudication with moderate or severe MRI findings of stenosis) 4.Fracture,previous spine surgery,neuromuscular disease of the trunk,malignancy,infections, or pregnancy 5.corticosteroid injection(epidural or facet) within past 3 months. 6.Contraindications of MRI 7.Allergy or intolerance to local anesthetic/steroid. 8.patients having systemic arthritis viz rheumatoid arthritis,ankylosing spondylitis,gout arthritis

Design outcomes

Primary

MeasureTime frame
Pain relief in low back painTimepoint: Pre op,Immediate postop,15days,1st month,3rd month,6th month

Secondary

MeasureTime frame
Improvement in multifidus muscle motility and thicknessTimepoint: Pre op,Immediate postop,15days,1st month,3rd month,6th month

Countries

India

Contacts

Public ContactDr Nimisha Verma

Institute of medical sciences,BHU

verma.nimisha5@gmail.com221005

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026