Health Condition 1: G360- Neuromyelitis optica [Devic]
Conditions
Interventions
Intervention1: Plasma Exchange: Plasma exchange will be performed at the bedside on the enrolled patients in neurology ward (Department of neurology) on alternate days, using a continuous flow centrif
Sponsors
Post Graduate Institute of Medical Education and research Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age more than 18 years 2. Presented with an acute attack of NMOSD 3. Willing to give informed consent for inclusion in the study
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. Known allergic to plasma proteins 3. Mechanically ventilated patients 4. Patients with systemic autoimmune disorders (RA, SLE, etc) 5. Patients positive for viral markers like HBsAg, anti-HIV , anti-HCV and covid-19 positive by RT-PCR.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in â??Expanded Disability Status Scaleâ?? scoreTimepoint: as assessed on day 10 and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change in â??Activities of Daily Living scaleâ?? score 2. Changes in MRI findings 3. Functional assessment (clinical) Timepoint: as assessed on day 10 and 12 weeks | — |
Countries
India
Contacts
Public ContactGarima Siwach
PGIMER,Chandigarh
Outcome results
None listed