Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: 1.Dexmedetomidine
2.Ketamine
3.Tramadol: These 3 drugs, dexmedetomidine 0.5mcg/kg, ketamine 0.25mg/kg, tramadol 0.5mg/kg will be diluted to a volume of 5 ml in a 5 ml syringe and admini
Sponsors
Dr Tanwin Khan
Eligibility
Inclusion criteria
Inclusion criteria: Patientâ??s undergoing elective surgery under spinal anaesthesia and with valid consent ASA-1 and 2 Age 18-65 yrs Height â?? 140- 180cms Lower limb surgeries Lower abdominal surgeries
Exclusion criteria
Exclusion criteria: Patient refusal ASA- 3 & 4 Age 65yrs Drug allergy Compromised cardio- respiratory functions Renal or hepatic disease Thyroid disorders Psychiatric disorder Severe diabetes or autonomic neuropathies Known history of substance or alcohol abuse Pregnant patients Obese (body mass index >30kg/m2) Contraindications to spinal anaesthesia Patients having visual analogue scale (VAS) >6 intra-operatively and were offered general anaesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All the drugs i.e, dexmedetomedine, ketamine and tramadol decrease the shivering under spinal anesthesia compared to normal saline in their lowest possible doses used Timepoint: wrench shivering grades 1 and 2 are managed conservatively and grades 3 and 4 are treated with pethidine | — |
Secondary
| Measure | Time frame |
|---|---|
| side effects of drugs dexmedetomidine(sedation), ketamine(increased arterial blood pressure) and tramadol(nausea and vomitings) are studiedTimepoint: sedation is assessed with filos grading and grade 3 and 4 are considered positive | — |
Countries
India
Contacts
Public ContactDrTanwin Khan
Nizams Institue of Medical Sciences
Outcome results
None listed