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EFFECTIVENESS OF TITANIUM-PREPARED PLATELET RICH FIBRIN (T-PRF) IN TREATMENT OF PERIODONTAL DISEASE.

COMPARATIVE EVALUATION OF EFFECTIVENESS OF TITANIUM-PREPARED PLATELET RICH FIBRIN (T-PRF) IN COMBINATION WITH OPEN FLAP DEBRIDEMENT AND OPEN FLAP DEBRIDEMENT ALONE ASSESSED BY CONE BEAM COMPUTED TOMOGRAPHY IN TREATMENT OF PATIENTS WITH INTRABONY DEFECTS: A RANDOMIZED CLINICAL TRIAL.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029879
Enrollment
30
Registered
2020-12-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A00-B99- Certain infectious and parasitic diseases Health Condition 2: K053- Chronic periodontitis

Interventions

Intervention1: Titanium prepared Platelet rich fibrin(T-PRF): Patients allocated to this group will be treated with titanium prepared platelet rich fibrin in combination with open flap debridement. Co

Sponsors

DrApeksha Gajghate
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients. 2.Patients with localized and generalized chronic periodontitis with three-walled intrabony defects. 3.Full mouth plaque scores should be less than 15 %.

Exclusion criteria

Exclusion criteria: 1.Patients who underwent periodontal therapy within 1 year. 2.Teeth indicated for extraction. 3.Patients having habit of consuming tobacco in any form. 4.Pregnant and lactating women. 5.Patients on any drug therapy which may affect the outcome of present study

Design outcomes

Primary

MeasureTime frame
1.Probing Pocket Depth (PPD) 2.Relative Attachment level (RAL) 3.Gingival Recession (GR) 4.Plaque Index (PI) (Silness and Loe 1964) 5.Gingival Index (GI) (Loe and Silness 1963). Timepoint: Pre-operatively and post-operatively at 6 months.—

Secondary

MeasureTime frame
Assessment of defect volume by Cone beam computed tomography (CBCT)Timepoint: pre-operatively and post-operatively at 6 months—

Countries

India

Contacts

Public ContactDrSalman Ansari

Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur.

agajghate.ag@gmail.com09730099379

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026