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Compare inhalational agent sevoflurane versus betablocker for controlling heart rate and blood pressure response to surgical stress in laparoscopic surgery

Comparison between sevoflurane bolus and esmolol bolus for attenuating hemodynamic response to pneumoperitoneum in laparoscopic surgery- A prospective randomised study. - SEVOBOLUS

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029853
Enrollment
60
Registered
2020-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: BOLUS DOSE OF SEVOFLURANE INHALATIONAL AGENT: After induction readings of HR,SBP,DBP,MAP ,inspiratory & expiratory sevoflurane will be taken. After appropriate positioning and before in

Sponsors

Ruby Hall Clinic
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • ASA PS I • 18 - 60 years of age • Male and Female • Elective procedure under GA • Mallampati airway class I &II

Exclusion criteria

Exclusion criteria: • Patient on beta-blockers • Obese • Difficult airway • Severe Anaemia • Allergic to drugs in the study

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness of Esmolol bolus and Sevoflurane bolus for controlling pressor response like heart rate,systolic BP,diastolic BP & Mean artereial pressure Timepoint: Every minute for 10 minutes after the bolus of sevoflurane and esmolol in either group—

Secondary

MeasureTime frame
To determine any adverse effects in either group To study time taken to control pressor response in either group Timepoint: every minute hemodynamic parameters recorded for 10 minutes—

Countries

India

Contacts

Public ContactSHEKH MOHIDEEN MAHEBUB

Ruby hall clinic, pune

drnita610@yahoo.com09823721982

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026