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Effect of oral B-12 and B-complex Vitamins in Nerve function recovery after surgery in the lower jaw bone.

Effect of Oral Methylcobalamin and B - complex Vitamins in the regeneration of Inferior alveolar nerve following post-surgical neurosensory deficit after Bilateral sagittal split osteotomy and mandibular impaction surgeries- A Randomised multi-centric study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029807
Enrollment
44
Registered
2020-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G974- Accidental puncture and lacerationof a nervous system organ or structure during a procedure

Interventions

Intervention1: Methycobalamine: 500 mcg orally once daily for three months Control Intervention1: B-Complex Vitamins: B1-10 mg,B2-10 mg,B3-45 mg,B5-50 mg, B6-3mg, B12-15 mcg once daily for three month

Sponsors

Suresh Vyloppilli
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of both sexes between 18-30 Years of Age 2. Routine surgeries for impacted mandibular third molar removal and bilateral sagittal split osteotomies with a post-operative sensory deficit in areas supplied by Inferior alveolar nerve. 3. All the cases of the post-op sensory deficit without visible transection of the inferior alveolar nerve during surgery

Exclusion criteria

Exclusion criteria: 1) Patients with existing diabetic and other neural disorder, pre-existing inferior alveolar nerve deficit. 2) Patients unwilling to commit a long follow up term. 3) Patients with visible transection of the inferior alveolar nerve at the time of surgery.

Design outcomes

Primary

MeasureTime frame
1.Assess the effect of oral methylcobalamin 2.Assess the effect of oral B-complex vitamin.Timepoint: one week, one month, three months, six months, nine months and one year—

Secondary

MeasureTime frame
Evaluation of blood levels of methylcobalamin Timepoint: Three Months—

Countries

India

Contacts

Public ContactShankar Vinod Vichattu

RMDCH, Annamalai university

omfsvat@gmail.com9443244213

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026