Study of bone gain in Periodontitis patients having bone defect when treated with decortication along with platelet rich fibrin

A clinical and radiographic evaluation of open flap debridement followed by intramarrow penetration with and without platelet rich fibrin in treatment of intrabony defects in periodontitis patients-A randomized clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/12/029768

Enrollment

Registered

2020-12-14

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Periodontal flap surgery: Open flap surgical procedure with intramarrow penetration and platelet rich fibrin in periodontal intrabony defects Control Intervention1: Periodontal flap sur

Eligibility

Inclusion criteria

Inclusion criteria: 2. Patient diagnosed with stage II and stage III periodontitis as per world workshop jointly held by the American Academy of Periodontology’s and European Federation of Periodontology International Workshop for Classifications of Periodontal Disease 2017. 3. Intrabony defect in both maxillary and mandibular region. 4. Patients having at least one intrabony defect =3 mm along with attendant periodontal pocket depth =5mm and tooth mobility not greater than grade II And Subjects having acceptable systemic health. 5. Participants must have completed initial periodontal therapy scaling root planing consisting of plaque control and good oral hygiene 6. Adequate width of keratinized gingiva should be present. 7. Absence of overt clinical inflammation at the time of surgery. 8. Teeth should be present on both sides of intrabony defects for preparation of stent. 9. Patient signing written informed consent.

Exclusion criteria

Exclusion criteria: 1. Medically compromised patients, mentally challenged person. 2. With unacceptable oral hygiene (PI >2) 3. Patients who had received any type of periodontal therapy for the past 6 months with a known history of allergy to Chlorhexidine or any other medicine are used in the study. 4. Patients taking any immuno-suppressive drugs like corticosteroids and with any metabolic disease or endocrine disease having direct or indirect influence on bone healing. 5. Patients with intrabony defects showing radiographic extension beyond the root apices along with positive signs and symptoms of endodontic pathology will be excluded 6. Patient on anticoagulant therapy or with bleeding disorders 7. Patient on active orthodontic treatment and Endodontically treated teeth. 8. Patients with bone disorders and / or who are on bisphosphonate therapy. 9. Pregnant and lactating women. 10. Presence of defective prosthesis in the area of interest. 11. Subjects who are smokers and consume tobacco in any form.

Design outcomes

Primary

Measure	Time frame
Treatment outcomes of open flap debridement followed by intramarrow penetration along with platelet rich fibrin is better than open flap debridement followed by intramarrow penetration without using platelet rich fibrin as evaluated by changes in clinical parameters.Timepoint: Three months, Six months postsurgey	—

Secondary

Measure	Time frame
reatment outcomes of open flap debridement followed by intramarrow penetration along with platelet rich fibrin is better than open flap debridement followed by intramarrow penetration without using platelet rich fibrin as evaluated by changes in radiographic parameters.Timepoint: Three months, Six months postsurgery	—

Countries

India

Contacts

Public ContactDr Gauri Ugale

MIDSR Dental College Latur

drrohinimale1912@gmail.com9325000850

Outcome results