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Supine vs Prone in non-ventilated patients with respiratory failure

Supine vs Prone position in non-ventilated patients with mild to moderate ARDS â?? A feasibility study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029702
Enrollment
60
Registered
2020-12-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: Prone Postion: Awake prone position for at least 6 hours a day with pillows to comfort Control Intervention1: Supine position: Usual care

Sponsors

Apollo Hospitals Education and Research Foundation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: >18 years Type 1 respiratory failure SpO2 >92% on 4litres or more oxygen or PF ratio PCO2 Patients with hemodynamic shock requiring norepinephrine

Exclusion criteria

Exclusion criteria: Pregnant women PCO2 >45mmHg Patients with hemodynamic shock requiring norepinephrine >= 0.1 mcg/kg/min GCS Patients who need immediate intubation Spinal instability Life threatening cardiac arrhythmias

Design outcomes

Primary

MeasureTime frame
The primary outcome measure is the proportion of patients adhering to the protocol in each groupTimepoint: 2 weeks

Secondary

MeasureTime frame
Secondary outcome measures include total number of patients recruited per week, failure of oxygen therapy leading to escalation of respiratory support, number of hours prone and the total number of prone sessions in a day, length of stay in the ICU, hospital length of stay, mortalityTimepoint: at 2 weeks and 4 weeks

Countries

India

Contacts

Public ContactDevachandran Jayakumar

Apollo Speciality Hospital

deva@icuconsultants.com09566185114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026