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A meta-analysis of individual patient data using Ki-67 proliferative index to see long-term effect in surgically treated intracranial meningioma patients.

Ki-67 proliferative index for tailoring long-term follow-up in surgically treated intracranial meningioma patients: a meta-analysis of xxx individual patient data - KiM Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/12/029687
Enrollment
5000
Registered
2020-12-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C709- Malignant neoplasm of meninges, unspecified

Interventions

None listed

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Eligible patients comprise patients in which the covariates of interest are known. 2. The minimum data requirements comprise data on recurrence (+ recurrence-free survival time), overall survival (+ overall survival time), extent of surgical resection, age, sex, WHO grade and Ki67 percentage. Information on adjuvant radiotherapy and location will also be sought but such missing data does not lead to exclusion of that specific patient.

Exclusion criteria

Exclusion criteria: 1. Patients whose minimum required data is unavailable.

Design outcomes

Primary

MeasureTime frame
Correlation of Ki-67 index with time to recurrence.Timepoint: Survival will be assessed at 5 years from diagnosis.—

Secondary

MeasureTime frame
1) Progression free survival 2) Overall survivalTimepoint: Survival will be assessed at 5 years from diagnosis.—

Countries

Albania, Brazil, Canada, China, Croatia, Denmark, Egypt, France, Germany, Hungary, India, Italy, Japan, Norway, Portugal, Slovenia, Spain, Turkey, United Kingdom, United States of America

Contacts

Public ContactDr Tejpal Gupta

Tata Memorial Hospital

tejpalgupta@rediffmail.com02224177000

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026