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Remineralization efficacy of CPP-ACP with Fluoride versus Sodium Fluoride mouthrinse on white spot lesions among orthodontic patients

Remineralization efficacy of CPP-ACP with Fluoride versus Sodium Fluoride mouthwash on white spot lesions among orthodontic patients- A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029661
Enrollment
52
Registered
2020-12-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: GC TOOTH MOUSSE PLUS: GROUP A will be given GC Tooth Mousse Plus and will be instructed to brush with a fluoride toothpaste in the morning and night and then 1.Apply a pea size amount

Sponsors

Self funded Dr Soumya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Orthodontic patients with fixed orthodontic appliances on the facial surface of the maxillary and mandibular incisors, and canines. 2.Subjects of 12 years age or above. 3.Subjects with atleast two active white spot lesions (Nyvad criteria) on the facial surface of the maxillary, mandibular incisors and canine at the time of recruitment of study subjects. 4.Subjects with verifiable records of bonding with non-sealing and non-fluoride releasing bonding agents/cements. 5.Subjects with at least 12 months of fixed appliance therapy remaining from the time of recruitment.

Exclusion criteria

Exclusion criteria: 1.Subjects with milk protein allergy, 2.Subjects with untreated cavitated lesions or extensive restorations on the facial surfaces of the study teeth, 3.Subjects with intrinsic or extremely heavy extrinsic staining on facial surface of the maxillary, mandibular incisors and canine. 4.Subjects with moderate to severe fluorosis, 5.Subjects with dental morphologic/ anatomical/developmental anomalies 6.Subjects with any medical illness/or on any medications for dental or systemic disease. 7.Planned to relocate or move within 6 months of enrolment.

Design outcomes

Primary

MeasureTime frame
Remineralization efficacy of CPP-ACP with Fluoride in terms of EDI and ICDAS scoresTimepoint: Baseline, 1st week , 2nd week , 3rd week , 1 month , 2nd month and 3rd month

Secondary

MeasureTime frame
NATimepoint: NA

Countries

India

Contacts

Public ContactDr CM Marya

Sudha Rustagi College of Dental Science and Research

drruchinagpal1975@gmail.com9811415169

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026