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what intranasal dexmedetomidine dose is better in sedation : 2mcg/kg or 3mcg/kg?

Comparison of two different doses of intranasal dexmedetomidine for pediatric procedural sedation: a prospective study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029649
Enrollment
200
Registered
2020-12-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: There are two intervention arms, intranasal dexmedetomidine 3mcg/kg and intranasal dexmedetomidine 2mcg/kg.: Duration approximate 2 hours

Sponsors

All India Institute of Medical Sciences Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: pediatric patients aged between 1 years and 10 years who are undergoing non-invasive radiological procedures like CT scan, MRI, Ultrasound, echocardiography. Belonging to ASA PS grade 1 and 2.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Research Hypothesis: Intranasal Dexmedetomidine 3mcg/kg is more efficient than intranasal dexmedetomidine 2mcg/kg for non-invasive radiological procedural sedation in pediatric age group. Greater efficacy will be established based on sedation level and need of rescue doses of drug.Timepoint: One year

Secondary

MeasureTime frame
we assume that, physician�s satisfaction in performing the procedure is better with 3mcg/kg body weight safety profile of 3mcg/kg body weight dose of Intranasal dexmedetomidine in terms of adverse events (bradycardia, hypotension, desaturation, excessive sedation) is better. Timepoint: 8 months

Countries

India

Contacts

Public ContactSuresh Nagalikar

All India Institute of Medical Sciences, Raipur

drsamar0002@gmail.com8014910806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026