FindTrial
Sign In

Assessment of the changes in brainâ??s blood flow using a CT scan procedure called perfusion CT imaging before and following temporary and partial resection of skull to reduce brain swelling in large, life threatening brain damage due to occlusion of an artery called middle cerebral artery.

Assessment of Changes in Cerebral Blood Flow Following Decompressive Craniectomy in Patients With Malignant Middle Cerebral Artery Infarct by Perfusion CT Imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/12/029645
Enrollment
35
Registered
2020-12-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G819- Hemiplegia, unspecified

Interventions

Intervention1: nil: nil

Sponsors

Sreekesh P V
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants with clinical and radiological features suggestive of malignant middle cerebral artery infarct (infarct involving >50 % of middle cerebral artery territory or presence of midline shift >5mm on plain CT scan or fall in admission GCS by 1 point) who undergo decompressive craniectomy within 48 hours of ictus.

Exclusion criteria

Exclusion criteria: 1.Participants with deranged renal parameters and history of radiocontrast allergy 2.Participants who are unfit for surgery. 3.Participants who are pregnant. 4.Participants with previous history of stroke. 5.Participants with intracerebral hemorrhage on initial CT scan.

Design outcomes

Primary

MeasureTime frame
Perfusion CT parameters 1.Mean Transit Time (MTT) 2.Cerebral Blood Flow (CBF) 3.Cerebral Blood Volume (CBV) Timepoint: Before and within 24 hours after decompressive craniectomy—

Secondary

MeasureTime frame
30day outcome by modified Rankin ScaleTimepoint: 30 days after decompressive craniectomy—

Countries

India

Contacts

Public ContactSreekesh P V

JIPMER,Puducherry

asrameshms@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026