Health Condition 1: H160- Corneal ulcer
Conditions
Interventions
Intervention1: Use of Tigecycline eye drop: Each infected eye will be be treated with Tigecycline 1% and Azithromycin ointment 1% and Tab azithromycin 500 mg twice a day.
Control Intervention1: NA: NA
Sponsors
L V Prasad Eye Instituta
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age equal to or more than 18 years. 2) Male or female 3) Stromal infiltrate size between 2-8 mm. 4) Corneal scraping positive for Aseptate broad ribbon like filaments characteristic of Pyhthium in direct smear examination by any one or more of the methods used.
Exclusion criteria
Exclusion criteria: 1) The corneal scrapings are negative for Pythium 2) The patient has a history of allergy to any of drugs used. 3) The cornea or sclera has been perforated or perforation is impending.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing of keratitiesTimepoint: 1 week, 2 week, 3 week, 1 month, 3 month, 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity, number of PK requiredTimepoint: 1 week, 2 week, 3 week, 1 month, 3 month, 6 month | — |
Countries
India
Contacts
Public ContactDrBhupesh Bagga
L V Prasad Eye Institute
Outcome results
None listed