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TO STUDY THE EFFICACY OF MADHUPIPPALYADI YOGA PRATISARANA, NISHADI TAILA KAVALA AND RASAYANA YOGA ORALLY IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS

FURTHER STUDY ON THE EFFICACY OF MADHUPIPPALYADI YOGA PRATISARANA, NISHADI TAILA KAVALA WITH AND WITHOUT RASAYANA YOGA ORALLY IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS – AN OPEN LABELLED RANDOMISED COMPARATIVE CLINICAL TRIAL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029592
Enrollment
40
Registered
2020-12-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T658- Toxic effect of other specified substances

Interventions

Intervention1: 1.Madhupippalyadi Yoga Prathisarana 2.NishadiTaila Kavala 3.RasayanaYoga orally : Drug (A) : Madhupippalyadi Yoga Dose : 3-6gms BD locally as Prathisarana Time : 100-200 Matra (2-4

Sponsors

th flInstitute of post graduate teaching and research in ayurveda gujarat ayurved university
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.The patients having clinical signs and symptoms: Blanching and stiffness of oral mucosa, altered taste sensation ,altered salivation, repeated vesicular eruption and ulceration on buccal mucosa, palate and pillars, burning sensation in mouth, intolerance to eat hot and spicy foods, difficulty in opening mouth. 2.Interincisal distance of more than 15mm.

Exclusion criteria

Exclusion criteria: 1.Age less than 18 years and more than 60years. 2.Extensive fibrosis of all the oral mucosa, severe trismus with an interincisal distance of less than 15 mm. 3.Disease most advanced with premalignant and malignant changes. 4.Oral manifestation of scleroderma. 5.Oral lichen planus. 6.Chronic debilitating conditions like DM, HTN.

Design outcomes

Primary

MeasureTime frame
relief in signs and symptoms of oral submucous fibrosisTimepoint: 45 days

Secondary

MeasureTime frame
de addiction from mawa masala , gutka and other such irritating chewing substances and improving oral healthTimepoint: by completion of study

Countries

India

Contacts

Public ContactDr D B Vaghela

Institute of post graduate teaching and research in ayurveda

drvaghela@rediffmail.com9825407899

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026