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: Serial sero-epidemiological surveillance study to monitor the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the Vellore Demographic Health Surveillance System (HDSS)

A Cohort Study to study SARS-CoV-2(Severe Acute Respiratory Syndrome Corona Virus), Dengue, Chikungunya in India

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/12/029564
Enrollment
5000
Registered
2020-12-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Dr Winsley Rose
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: all individuals currently residing and likely to stay in the area till the end of study (1 year) in the study area will be considered eligible for inclusion.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

MeasureTime frame
I. Estimate the sero-prevalence of SARS-CoV-2 infection in the general population II. Estimate the 4 monthly incidence of SARS-CoV-2 infection based on serial sero-surveys III. Estimate cumulative sero-conversion of SARS-CoV-2 infection over one year period IV. Estimate the sero-prevalence and annual sero conversion of Dengue and Chikungunya in a sub sample of the study Timepoint: serosurvey will be done once in 3 months for a period of one year—

Secondary

MeasureTime frame
I. Monitor the trend of SARS-CoV-2 transmission in the general population II. Determine the prevalence and incidence of SARS CoV2 sero-positivity among the members of the households with at least one seropositive individual (clustering of infection at household level)Determine the risk factors for SARS-CoV-2 infection III. Determine the duration of persistence of antibodies in individuals tested positive for SARS-CoV-2 infection Timepoint: serosurvey will be done once in 3 months for a period of one year—

Countries

India

Contacts

Public ContactWinsley Rose

Christian Medical College, Vellore

winsleyrose@gmail.com04162283343

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026