FindTrial
Sign In

Comparison Of Effects Of Pregabalin and Clonidine On Pain, Sedation and Recovery From General Anesthesia After Laparoscopic Hysterectomy

A Comparative Study Of Effects Of Oral Pregabalin Versus Oral Clonidine As Premedication On Early Post-Operative Pain, Sedation And Recovery Score In Patients Posted For Laparoscopic Hysterectomy Under General Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029541
Enrollment
90
Registered
2020-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N95- Menopausal and other perimenopausal disorders

Interventions

Intervention1: Tab pregabalin: Preemptive use of single dose tablet pregabalin(75 mg) given orally with a sip of water 60 minutes prior to induction of general anaesthesia. Intervention2: Tab Clonidin

Sponsors

Institute of Medical Sciences And SUM Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA Grade-I status 2. Patients posted for elective laparoscopic hysterectomy

Exclusion criteria

Exclusion criteria: 1. Refusal of the patient to participate in the study 2. Patients belonging to ASA Grade II/III/IV status 3. Any known allergies to Clonidine or Pregabalin 4. Patients with any chronic pain syndrome under treatment with any GABAergic drugs 5. Patients in whom laparoscopy was converted to laparotomy

Design outcomes

Primary

MeasureTime frame
Degree of pain assessed by 10-point Visual Analogue Scale (VAS)Timepoint: At baseline, 1, 2, 4, 6, 12 and 24 hours respectively.—

Secondary

MeasureTime frame
Degree of Sedation measured by Ramsay Sedation Scale(RSS)Timepoint: At baseline, 6, 12 and 24 hours respectively.;Recovery measured using Modified Aldrete scoreTimepoint: Before discharge to ward from the recovery room—

Countries

India

Contacts

Public ContactEESHA BANERJEE

INSTITUTE OF MEDICAL SCIENCES AND SUM HOSPITAL

dr.diptimayee2010@gmail.com9861159151

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026