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A Study to determine the efficiency of a specific modality of ultrasound (tissue doppler imaging) in imaging an abddominal muscle (diaphragm) to predict if patients can be successfully liberated from ventilator

Efficacy Of Diaphragmatic Tissue Doppler Imaging Parameters In Predicting Weaning Outcomes In Critically Ill Patients A prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/12/029533
Enrollment
40
Registered
2020-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J989- Respiratory disorder, unspecified

Interventions

None listed

Sponsors

Gautham Chandran
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: On mechanical ventilation >48hrs. Readiness for weaning from mechanical ventilation Recovery from the cause of respiratory failure Stable hemodynamic parameters. Low or no vasopressor requirement No sedative agents or NMBA > 24 h before enrolment. Patients who meet criteria for spontaneous breathing trial Fio2 Pressure Support (PS) Positive End Expiratory Pressure (PEEP) Respiratory Rate P/F ratio >200 Glasgow coma scale - GCS >14 , RASS: -2 to +2.

Exclusion criteria

Exclusion criteria: Pregnant Women Presence of Pneumothorax or Ascites H/o either neuromuscular disease, thoracic surgery, Diaphragmatic Palsy, Cervical Spine Injury Weaning failure definitely caused by upper airway obstruction Planned prophylactic NIV after extubation. Poor ultrasound windows and image

Design outcomes

Primary

MeasureTime frame
To determine the diagnostic accuracy of diaphragmatic pulse-wave tissue doppler imaging (PW-TDI) parameters in predicting weaning outcomes in critically ill mechanically ventilated patientsTimepoint: Ultrasound measurements will be taken at the end of a 60 minute spontaneous breathing trial—

Secondary

MeasureTime frame
Length of hospital stay. Timepoint: total duration of stay in hospital—

Countries

India

Contacts

Public ContactGautham Chandran

All India Institute Of Medical Sciences

bikashray.aiims@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026