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Efficacy of dexmedetomidine used during surgery for smooth recovery from general anaesthesia in laparoscopic surgeries.

Efficacy of continuous peri-operative infusion of dexmedetomidine for smooth emergence from general anaesthesia in laparoscopic surgeries.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029517
Enrollment
100
Registered
2020-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs Health Condition 2: R688- Other general symptoms and signs Health Condition 3: R688- Other general symptoms and signs

Interventions

Intervention1: Dexmedetomidine infusion will be continued till the extubation.: Continuous dexmedetomidine infusion will be given in study group till the extubation. Intervention2: Continuous Intraven
(20 minutes before the start of surgery) followed by continuous intravenous dexmedetomidine infusion at the rate of 0.4 mcg/kg will be given in study group till the time of administration of neostigm
(20 minutes before the start of surgery) followed by continuous intravenous dexmedetomidine infusion at the rate of 0.4 mcg/kg will be given in control group till pnuemoperitoneum will be deflated by

Sponsors

Shree Krishna hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA grade 1,2,3 physical status undergoing elective laparoscopic surgeries under general anaesthesia with estimated time of 1-3 hours.

Exclusion criteria

Exclusion criteria: 1)Known allergy for dexmedetomidine 2)Obese(BMI >35kg/m2) 3)Febrile 4)Pregnant females 5)Patients who is on antidepressants or opioid or non-opioid analgesics. 6)Pulse rate <60min

Design outcomes

Primary

MeasureTime frame
To observe the effect of IV dexmedetomidine on quality of emergence from general anaesthesia in terms of cough suppression and agitation.Timepoint: Post surgery at every 5 minutes( 0min, 5 min, 10 min, 15 min, 20 min, 25 min, 30 min)—

Secondary

MeasureTime frame
To observe the effect of IV dexmedetomidine on quality of emergence from general anaesthesia in terms of shivering and heamodynamics and time to extubation.Timepoint: Post surgery at every 5 minutes( 0min, 5 min, 10 min, 15 min, 20 min, 25 min, 30 min). Time to Extubation measured from switching off sevoflourane to removal of endotracheal tube.—

Countries

India

Contacts

Public ContactDr Kulin Shrimali

H.M.Patel center for medical care and Education

hemlatavk@charutarhealth.org9375031313

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026