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Comparing mechanical power in two commonly used breathing modes in children on Artificial breathing machine.

Randomized Controlled Trial to compare the mechanical dynamics of respiratory system in invasively ventilated children on Volume control and Pressure Regulated Volume Control Modes.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/12/029483
Enrollment
60
Registered
2020-12-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: VOLUME CONTROL MODE ON VENTILATOR: All patients freshly intubated shall be placed on Pressure Control (PC) mode on ventilator to begin with- PEEP titration, adjustments of FiO2 shall be

Sponsors

FARHAN A RASHID SHAIKH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children aged 1 month to 18 years who are intubated and placed on mechanical ventilation.

Exclusion criteria

Exclusion criteria: Children on NIV. Children who are hemodynamically unstable. Children who are already on High Frequency Oscillatory ventilation. Children with large pleural effusions, Children with ICD in situ, empyema, Ascites, Intra abdominal hypertension ( >12mmHg), Mediastinal mass. Refusal of consent to participate in study.

Design outcomes

Primary

MeasureTime frame
The Mechanical power and driving pressures calculated from the displayed parameters across the two modes (VC and PRVC) and at two tidal volumes (4ml/kg and 6ml/kg body weight) shall be compared.Timepoint: 18 months

Secondary

MeasureTime frame
The parameters of Peak inspiratory pressure, inspiratory time, Airway resistance, compliance shall be compared between the two modes of ventilators at two tidal volumes Impact of the modes on Saturation, Hemodynamics and patient comfort also shall be analyzed.Timepoint: 18 months

Countries

India

Contacts

Public ContactFARHAN A RASHID SHAIKH

Rainbow Children Hospital

drfarhan@rainbowhospitals.in9866007602

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026