Health Condition 1: L209- Atopic dermatitis, unspecified
Conditions
Interventions
Intervention1: Khadirarishta kaishor guggulu Gandhakadi Malahar: Khadirarishta 30ml BD after meals for 12 weeks kaishor guggulu 1gm tid (500mg/pill) for 12 weeks with lukewarm water Gandhakadi Malah
Sponsors
Central Council for Research in Ayurvedic sciences
Eligibility
Inclusion criteria
Inclusion criteria: Known cases of eczema (based on Hanifin and Rajka Criteria for Atopic Dermatitis/ Atopic Eczema) and willing and able to participate in the study
Exclusion criteria
Exclusion criteria: Patients with Status Eczematous condition. Patients with poorly controlled Hypertension ( >160/100 mmHg) Patients with uncontrolled Diabetes Mellitus having HbA1C > 8% Patients on medication with corticosteroids, phototherapy, biologics, antidepressants and any other drugs that may have an influence on the outcome of the study. Patients who have history of Atrial Fibrillation, Acute Coronary Syndrome, Myocardial Infarction, Stroke or Severe Arrhythmia in the last 6 months Symptomatic patients with clinical evidence of Heart failure Known cases of HIV and AIDS. Known cases of malignancy Patient taking participation in any other clinical trial. Women who are planning for conception / pregnant or lactating. Patients with concurrent serious hepatic disorders (defined as Aspartate Amino Transferase (AST) and / or Alanine Amino Transferase (ALT) > 2 times upper normal limit) or Renal Disorders (defined as S. Creatinine >1.2mg/dL), Severe Pulmonary Dysfunction (uncontrolled Bronchial Asthma and / or Chronic Obstructive Pulmonary Disease (COPD) H/o hypersensitivity to any of the trial drugs or their ingredients Patients who have completed participation in any other clinical trial during the past three months Any other condition which the Investigator thinks may jeopardize the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the clinical efficacy of Khadirarishta, Kaishoreguggulu and Gandhakadimalaharin Vicharchika (Eczema) by the assessmentof Change in Eczema Area Severity Index score (EASI)Timepoint: 14th day 28th day 42th day 56th day 70th day 84th day | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in clinical Sign & symptoms as per the Ayurvedic classics Changes in Patient Oriented Eczema measure (POEM) Changes in Dermatology Life Quality Index (DLQI) Questionnaire Timepoint: 14th day 28th day 42th day 56th day 70th day 84th day | — |
Countries
India
Contacts
Public ContactSavita Gopod
Regional Ayurveda Research Institute for skin disorders
Outcome results
None listed