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Reducing the stress Response to definite airway weaning with a Comparative Study Between Dexmedetomidine and Lignocaine drugs in patients who have undergone Surgery

Alleviating Haemodynamic Response to Tracheal Extubation: A Comparative Study Between Dexmedetomidine and Lignocaine in Surgical Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029326
Enrollment
60
Registered
2020-11-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

None listed

Sponsors

KMCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 20 to 65 years belonging to ASA 1 and ASA 2 undergoing elective surgical procedures in general surgery, gynaecology and ENT surgery with minimum anticipated duration of 60 minutes requiring endotracheal intubation were included in the study.

Exclusion criteria

Exclusion criteria: Patients with cardio-respiratory, renal, hepatic dysfunctions necessating post-operative mechanical ventilation, metabolic disorder, bleeding disorder, severe hypovolemia, neurological deficit, emergency surgery, morbid obesity, pregnancy, difficult airway and who are on antihypertensives, antiarrthymics, psychotropics and allergic medications to any drugs were excluded from the study.

Design outcomes

Primary

MeasureTime frame
The main aim of the study was to compare the effectiveness of single dose of Dexmedetomidine and Lignocaine in alleviating haemodynamic and airway responses during extubation and recovery. This study also focuses on the effects of drugs on observing the time to emergence and time to tracheal extubation, post-operative complications and undesirable effects of the study drug.Timepoint: Baseline, 1,2,3,4,5,10,15 minutes

Secondary

MeasureTime frame
This study also focuses on the effects of drugs on observing the time to emergence and time to tracheal extubation, post-operative complications and undesirable effects of the study drug.Timepoint: Baseline, 1,2,3,4,5,10,15 minutes

Countries

India

Contacts

Public ContactR Arun Kumar

Kovai Medical Center and Hospital Limited

ramab3068@gmail.com8277092979

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026