None listed
Conditions
Interventions
Intervention1: vitamin D 800 IU per day: Vitamin D supplementation will be started at discharge and continued till 14 weeks postnatal age.
Before hospital discharge, families will receive written inst
will be recorded for all the babies. The baby will be assessed for possible symptoms of Vitamin D toxicity (nausea, recurrent vomiting, poor feeding, abdominal pain, polydipsia, anorexia o
Sponsors
PGIMER CHANDIGARH
Eligibility
Inclusion criteria
Inclusion criteria: 1) Gestational age 37 weeks or more 2) Appropriate for gestation age (as defined by Intergrowth 21 growth charts) (32)
Exclusion criteria
Exclusion criteria: 1) Families are not willing to follow-up at PGIMER. 2) Mother or infant on medications which can affect vitamin D metabolism (33) (Annexure-VII) 3) Mother is a known case of Chronic renal failure/ chronic liver failure/Parathyroid disorders 4) Major congenital malformations 5) Severe birth asphyxia (As defined by AAP/ACOG or need for chest compression) 6) Enteral feeding is not established by 48 hours of life.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to compare proportions of vitamin D insufficieny in two groupsTimepoint: 14 weeks postnatal age | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of maternal and neonatal vitamin D deficiency and insufficiency 2. To compare the proportion of Vitamin D deficiency; biochemical parameters (serum Calcium, Phosphorous, ALP, PTH), anthropometry (Weight, Length, and Occipitofrontal circumference), adverse events related to vitamin D toxicity, and frequency of morbidities (episodes of respiratory illness, Hospitalization, seizure, etc) Timepoint: Outcome 1 at birth and rest at 14±2 weeks postnatal age | — |
Countries
India
Contacts
Public ContactJogender Kumar
PGIMER Chandigarh
Outcome results
None listed