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Response of patients and chest x-ray improvement after Remdesivir

Assessment of novel inflammatory, clinical and radiological response (â??Brixiaâ?? chest X ray score) to remdesivir in moderate and severe COVID-19 patients : a retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/11/029266
Enrollment
126
Registered
2020-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

Vishal Shanbhag
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18-90 years were included Patients who have been proven COVID-19 positive by reverse transcriptase polymerase chain reaction (RT-PCR),and the rapid antigen test. COVID -19 patients admitted between June 2020 and September 2020 Patients above 18 years admitted to hospital or critical care unit and on oxygen therapy, non-invasive ventilation (NIV) or invasive mechanical ventilation (IMV)

Exclusion criteria

Exclusion criteria: Patients with pre-existing liver disorders. 2. Patients with any prior hypoalbuminemic state. 3. Patients with hematological malignancies, immunocompromised states. 4. Patients with fluid resuscitations where the serum albumin level couldbe altered. 5. patients with trauma,extensive bowel resection,burns 6. Patients with AKI or CKD with possible albumin loss in urine

Design outcomes

Primary

MeasureTime frame
Correlation of CAR, NAR, CXR score after administration of remdesivir. SpO2, PaO2, FiO2, Pao2/Fio2 will be evaluated.Timepoint: Correlation of CAR, NAR, CXR score,at baseline and after 48hrs,72hrs,5days post administration of remdesivir. SpO2, PaO2, FiO2, Pao2/Fio2 will be evaluated at baseline and 48hrs,72hrs,5 days post administration of remdesivir

Secondary

MeasureTime frame
Days of hospital admission, outcome of hospital or ICU stay.Timepoint: 28 days after ICU admission

Countries

India

Contacts

Public ContactVishal Shanbhag

Kasturba medical College, Manipal

vishal.shanbhag@manipal.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 21, 2026