Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 40 -75 years Both genders Stable Diagnosed case of COPD Able to perform spirometry Group (B-D) COPD PATIENTS Consenting
Exclusion criteria
Exclusion criteria: Acute CHF/uncontrolled DM/ Severe uncontrolled HT / CLD /CRF / significant co-morbidity limiting acute life expectancy . Pregnant and lactating mothers . Acute exacerbation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PRIMARY OUTCOME-EXERCISE CAPACITY-6 MINUTE WALK DISTANCE SECONDARY OUTCOME-SPIROMETRY VARIABLES-FEV1/FEV1/FVC,PERIPHERAL MUSCLE DYSFUNCTION-MMT(MANUAL MUSCLE TESTING),SYMPTOM SCORE- (CAT)COPD ASSESSMENT TEST AND mMRC SCALE DYSPNEA SCALE,HEALTH RELATED QUALITY OF LIFE-SGRQ(ST.GEORGES RESPIRATORY QUESTIONNAIRE ),HOSPITAL ANXIETY AND DEPRESSION SCALE (HADS ) SCORE,EXACERBATION RATE, PR MONITORING AND HRV (HEART RATE VARIABILITY ),HOSPITALIZATION RATETimepoint: BASELINE, 3 MONTHS, 6 MONTHS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Spirometry Variables -FEV1/FEV1/FVC 2.Periphal Muscle Dysfunction-MMT (manual muscle testing) 3.Symptom score- (CAT) COPD Assessment Test and mMRC scale Dyspnea Scale 4.Health related quality of life –SGRQ (St. Georges Respiratory Questionnaire) 5.Hospital Anxiety and Depression Scale (HADS) score 6.Exacerbation rate 7.PR Monitoring and HRV (Heart Rate Variability) 8.Hospitalization rateTimepoint: baseline, 3 month,6 month | — |
Countries
India
Contacts
AIIMS RISHIKESH