To compare between nebulisation with dexmedetomidine and nebulisation with Ketamine as an accessory to nebulisation with lignocaine for awake fiberoptic intubation.

Comparative evaluation of Dexmedetomidine nebulisation and Ketamine nebulisation as an adjuvant to Lignocaine for awake fiberoptic intubation.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/11/029241

Enrollment

Registered

2020-11-19

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C069- Malignant neoplasm of mouth, unspecified

Interventions

Intervention1: Nebulisation: nebulisation with two different drugs Intervention2: nebulisation: patients will be nebulised with ketamine (3mg/kg) and dexmedetomedine (1mcg/kg) as an adjuvant to 6ml of

Eligibility

Inclusion criteria

Inclusion criteria: Patients with American Society of Anaesthesiology grading of 1 and 2. Patients having Mallampati grading of 3 and 4 and mouth opening less than 2 finger and also patients in whom neck extension is contraindicated.

Exclusion criteria

Exclusion criteria: patients with any type of AV block, bradycardia, hypotension, ventricular dysfunction, heart failure, coronary disease. patients with nasal pathology and recent epistaxis. allergy to drugs being used in the study patients not giving consent

Design outcomes

Primary

Measure	Time frame
to assess the ease of intubationTimepoint: to assess the ease of intubation using glottic score and cough score during bronchoscopy.	—

Secondary

Measure	Time frame
to assess the degree of sedation between two groups using Ramsay sedation score. to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period. to assess the complications encountered.Timepoint: to assess the degree of sedation between two groups using Ramsay sedation score during bronchoscopy. to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period. to assess the complications encountered that is all end points are recorded during the procedure..	—

Measure

Time frame

to assess the degree of sedation between two groups using Ramsay sedation score. to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period. to assess the complications encountered.Timepoint: to assess the degree of sedation between two groups using Ramsay sedation score during bronchoscopy. to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period. to assess the complications encountered that is all end points are recorded during the procedure..

—

Countries

India

Contacts

Public ContactDr Monica Kohli

king george medical university

monica_kohli@rediffmail.com9839041228

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026