Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: INTRAVENOUS VITAMIN C: 1 GRAM INTRAVENOUS VITAMIN C IV 8 HOURLY FOR 4 DAYS.
Control Intervention1: Placebo: SIMILAR LOOKING PLACEBO VIALS CONTAINING NS OR WATER FOR INJECTION IV 8 HOURL
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: All patients above the age of 18 years both males and females, admitted with a diagnosis of Moderate & Severe COVID -19 (on the basis of a positive RT-PCR report) at our facility during the study period (16/08/2020-15/12/2020)
Exclusion criteria
Exclusion criteria: 1. Patients with a known allergy to or adverse drug reaction with vitamin C. 2. Patients unable to provide consent or unwilling to participate in the study. 3. Patients participating in any other ongoing clinical trial will be excluded from the study. 4. Patients below the age of 18 years will be excluded from the study. 5. Pregnant or Breastfeeding Females will be excluded from the study. 6.Patients previously complicated with End-stage Lung Disease, End stage Malignancy, Glucose-6- Phosphate dehydrogenase deficiency, Diabetes Mellitus & Diabetic Ketoacidosis , Nephrolithiasis, Chronic Kidney Disease, Cardiogenic Pulmonary Edema will be Excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Clinical Recovery From the disease . 2. In Hospital Mortality .Timepoint: AT WEEKLY INTERVAL | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Improvement in Organ Failure Scores (APACHE & qSOFA Scores.). 2. Fall In level of Inflammatory Markers. 3. Improvement in Respiratory Index. 4. Duration on Mechanical ventilator. 5. Duration on Vasopressor Therapy.Timepoint: AT WEEKLY INTERVAL | — |
Countries
India
Contacts
Public ContactDR VIJAY KUMAR
AIIMS PATNA
Outcome results
None listed