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A clinical trial to study the effects of Pranayama in influencing the salivary level of Nerve Growth Factor (Protein) in individuals affected by Chronic periodontitis associated with type II Diabetes Mellitus.

Influence of Yogic Breathing on the Salivary level of Nerve Growth Factor in Chronic periodontitis with type II Diabetes â?? An Interventional study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029225
Enrollment
180
Registered
2020-11-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: Z00-Z99- Factors influencing health status and contact with health services

Interventions

Intervention1: yogic breathing: OM chanting - 10 minutes and Thirumoolar pranayama - 10 minutes Control Intervention1: comparison of NGF level followed by yogic breathing: comparison with healthy volu

Sponsors

Mahatmagandhi postgraduate institute of dental sciences
Lead Sponsor
DrVRAMESH DrSPKKENNEDY BABU DrRAJARATHINAM DrSVSRINIVASAN DrKRLENIN
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1) Systemically healthy individuals with generalized chronic periodontitis including both male and female between 30-60 years. 2) Patients diagnosed with type 2 diabetes mellitus (HbA1C above 7) at least one year prior to the commencement of the study. 3) Patients must have a minimal complement of 20 teeth, of which at least 30% of teeth must exhibit probing depth >= 4mm. 4) Patients who have not received anti-inflammatory drugs or antibiotics for the past 3 months. 5) Patients who have not received any kind of periodontal treatment for the past 6 months. 6) Patients who will maintain satisfactory oral hygiene. 7) Patients who are ready for subsequent follow up visits after periodontal treatment. 8) The control group will be composed of individuals with no evidence of interproximal attachment loss, probing depth

Exclusion criteria

Exclusion criteria: 1. History of any systemic disease other than type 2 diabetes mellitus. 2. Pregnant or lactating females. 3. History of smoking or any other form of tobacco use. 4. History of vitamin/mineral/antioxidant supplements intake during the last 3 months. 5. Patients who have undergone any periodontal treatment during the 6 months prior to the study.

Design outcomes

Primary

MeasureTime frame
measuring the effectiveness of pranayama in altering the level of Nerve growth factor in type 2 diabetes patientsTimepoint: NGF level at the base line and after 90 days followed by intervention—

Secondary

MeasureTime frame
measuring the periodontal status after pranayamaTimepoint: 1 year—

Countries

India

Contacts

Public ContactLenin

Mahatma gandhi postgraduate institute of dental sciences,govt. of puducherry institution,pondicherry

premalathakennedy@gmail.com9585545402

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026