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Gene variations in malaria related to Infection, Transmission and Drug response

Genetic factors of Plasmodium falciparum and Plasmodium vivax associated with Infection, Transmission and Drug response

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/11/029211
Enrollment
1050
Registered
2020-11-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B948- Sequelae of other specified infectious and parasitic diseases

Interventions

None listed

Sponsors

Manipal Academy of Higher Education
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria (Controls): Consenting individuals of male and female genders above 18 years. Healthy individuals with no history of malaria and other medical complications (G6PD deficiency, diabetic, Haemoglobinopathies, etc). Inclusion criteria (Case): Consenting individuals of all genders above 18 years. P. falciparum or P. vivax malaria-infected individuals.

Exclusion criteria

Exclusion criteria: Exclusion criteria (Controls): Participants of all genders below 18 years. Healthy individuals with a history of malaria. Participants with other medical complications (G6PD deficiency, diabetic, Haemoglobinopathies, etc) Exclusion criteria (Case): Participants of all genders below 18 years. Study participants with mixed Plasmodium infection and other medical conditions (G6PD deficiency, diabetic, Haemoglobinopathies, etc).

Design outcomes

Primary

MeasureTime frame
Gene variation and gene expression in parasite drug response genesTimepoint: First, second, third year

Secondary

MeasureTime frame
Identification of candidate gene in parasite to interrupt malaria transmissionTimepoint: Third year

Countries

India

Contacts

Public ContactDr TG Vasudevan

Manipal School of Life Sciences, MAHE, Manipal

saadi.a@manipal.edu9448984726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026