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Comparison of Effects and side effects between two variations of treatment modalities in Schizophrenia

Comparison of Efficacy and Cognitive Side Effect Profile Between Right Unilateral and Bilateral Ultra Brief Pulse ECT and Serum BDNF as Biomarker of Response in Schizophrenia: A Case Control Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029184
Enrollment
60
Registered
2020-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

Intervention1: Right Unilateral Ultra Brief Pulse ECT: Two Electrodes are placed over Right Temporal Region and Just Right to the Vortex Region of the Patient of Schizophrenia Receiving ECT Control In

Sponsors

Dr Sukriti Mukherjee
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i) Patients of either Sex aged between 18-60 years. ii) Right handed patients as assessed by Sidedness Bias Schedule (Mandal et al., 1992) iii) Diagnosis of Schizophrenia (F20.0 to F20.9) according to ICD 10, having clinical indication for Electroconvulsive therapy. iv) Patients giving written informed Consent.

Exclusion criteria

Exclusion criteria: i) Patients having predominant Catatonic symptoms ii) Any other Psychiatric comorbidity iii) Significant Neurological or Medical illness iv) Female patients who are Pregnant during the study period. v) Patients using any psychoactive substances in dependence pattern. (Except Caffeine and Nicotine) vi) Patients on Clozapine

Design outcomes

Primary

MeasureTime frame
Right Unilateral Ultra Brief Pulse ECT will have the same efficacy as Bilateral Ultra Brief Pulse ECT in Schizophrenia patientsTimepoint: 2 weeks

Secondary

MeasureTime frame
Right Unilateral Ultra Brief Pulse ECT will have better cognitive side effect profile compared to Bilateral Ultra Brief Pulse ECT in Schizophrenia patientsTimepoint: 2 weeks

Countries

India

Contacts

Public ContactDr Sailendra Kumar Deuri

LGBRIMH

director@lgbrimh.gov.in03712232652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026