Health Condition 1: M958- Other specified acquired deformities of musculoskeletal system
Conditions
Interventions
Intervention1: combined dexamethasone and dexmeditomidine IV: intravenous dexamethasone 0.11mg per kg and dexmeditomidine 1mcg/kg will be given along with block
Control Intervention1: control group: i
Sponsors
SRI manakula vinayagar medical college hospital RESEARCH FUND
Eligibility
Inclusion criteria
Inclusion criteria: Patients who are scheduled for upper limb fracture (elbow, forearm) fixation surgery Patients with American Society of Anesthesiologists Physical Status Classification (ASA) I and II of age 18-70 years belonging to both genders
Exclusion criteria
Exclusion criteria: Chronic pain disorder Pregnancy Refusal to participate in the study History of cardiac, renal, hepatic disease History of uncontrolled diabetes mellitus Preexisting neurological deficits or neuropathy affecting the brachial plexus Contraindications to peripheral nerve block (coagulopathy, block needle site infection) Allergy or hypersensitivity to local anesthetics. Block failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare time to first analgesic requirement in all 4 groups (control group, IV dexamethasone group, IV dexmedetomidine group, Combined IV dexamethasone and IV dexmedetomidine group)Timepoint: 24-48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of motor blockade Duration of sensory blockade 1. Pain severity at 6, 12, 18 and 24 h postoperatively using VAS score 2. Cumulative postoperative tramadol and paracetamol dose used in 24 hours 3. Dexmedetomidine related side effects (hypotension, bradycardia and sedation), 4. Dexamethasone related side effects (increasing blood sugar, perineal pruritus, surgical site infection and delayed wound healing). Timepoint: 24-48 hours | — |
Countries
India
Contacts
Public ContactSRINIVASAN R
SRI MANAKULA VINAYAGAR MEDICAL COLLEGE HOSPITAL
Outcome results
None listed