Health Condition 1: I998- Other disorder of circulatory system
Conditions
Interventions
Intervention1: Balanced crystalloids: After treating physician decided that patient requires IV fluid this group will recieve Balanced crystalloid (plasmalyte) as IV fluid.
Control Intervention1: Isot
Sponsors
Sir Gangaram Hospital New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Age 1month to 18 years patients â??Requiring IV fluids bolus for hypo-perfusion and/or hypotension as per discretion of treating clinician at admission or within 48 hours of admission â??Patients requiring IV maintenance fluids.
Exclusion criteria
Exclusion criteria: All the patients â??With burns, following liver transplant surgery. â??Preexisting electrolyte abnormality or requirement of dialysis. â??Diabetic ketoacidosis. â??Congenital or acquired cardiac disease. â??Known acute or chronic renal disease. â??On diuretics or carbonic anhydrase inhibitors â??Admitted on vasoactive drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the occurrence of chloride disturbance and hyperchloremia with the use of balanced crystalloids versus isotonic saline as resuscitation and maintenance fluids in critically ill children admitted over period of 48 hours.Timepoint: 48 hour post admission | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Sodium potassium disturbances. 2.Acid-base disturbances 3.The incidence of Acute renal injury in first 48 hours in PICU as defined by KDIGO criteria 4.The need and duration of RRT during the hospital stay 5.Proportion of patients treated with and duration of treatment with vasoactive drugs. 6.Duration of mechanical ventilation 7.Duration of PICU and hospital stay 8.All- cause mortality during PICU and hospital stay. Timepoint: Till 48 hours after admission and till discharge from hospital. | — |
Countries
India
Contacts
Public ContactDr Sapana Jain
Sir Gangaram Hospital
Outcome results
None listed