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Comparison of effect of Propofol, Thiopentone and Etomidate on Anesthesia Induction Time, Blood pressure rise due to Intubation and Recovery Time from these agents in Laparoscopic Surgeries under General Anaesthesia

Comparative Evaluation of Propofol, Thiopentone and Etomidate on Induction Time, Intubation Response and Recovery Time in Laparoscopic Surgeries under General Anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029093
Enrollment
120
Registered
2020-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Induction with Propofol: Anesthesia shall be induced with Propofol 2mg/kg IV Control Intervention1: Induction with thiopentone: Induction will be done with thiopentone 5 mg/kg IV Contro

Sponsors

Dr Sooshrut Thakur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The study will be conducted in normotensive adult patient ASA I & II

Exclusion criteria

Exclusion criteria: 1. Patients with anticipated dif�cult intubation. 2. Patients with history of drug allergy to drugs under study i.e. history of allergy to egg proteins. 3. Refusal of consent by patient. 4. History of acute intermittent porphyria. 5. History of alcoholism and drug addiction. 6. Patients with increased risk of regurgitation of gastric contents e.g. hiatal hernia, pregnancy, intestinal obstruction. 7. Patient who are anemic, hypoproteinemic, jaundiced.

Design outcomes

Primary

MeasureTime frame
Systolic Blood PressureTimepoint: 0 min 1 min 3 min 5 min 10 min 15 min 20 min 25 min 30 min 35 min 40 min 45 min 50 min 55 min 60 min

Secondary

MeasureTime frame
Loss of eyelash reflexTimepoint: 0 min 1 min 3 min 5 min;Recovery score (steward) equal to or more than 6 achievedTimepoint: 5min 10minutes 15minutes 20minute 25 min 30 min

Countries

India

Contacts

Public ContactSooshrut Thakur

Indira Gandhi Medical College, Shimla

aartisharma309@gmail.com9418299888

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026