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Role of dural sealant in prevention of cerebrospinal fluid (CSF) leak

Does use of a dural sealant during endoscopic endonasal repair of dural defect prevent cerebrospinal fluid (CSF) leak?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029077
Enrollment
60
Registered
2020-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G960- Cerebrospinal fluid leak Health Condition 2: G969- Disorder of central nervous system, unspecified Health Condition 3: G968- Other specified disorders of central nervous system

Interventions

Intervention1: Use of dural sealant: A dural sealant will be used during surgery. Control Intervention1: No use of dural sealant: No dural sealant will be used in the surgery

Sponsors

Sanjay Gandhi Postgraduate Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All cases of skull base lesions and CSF rhinorrhea operated by endonasal endoscopic approach

Exclusion criteria

Exclusion criteria: • Recurrent cases • Children below 5 years

Design outcomes

Primary

MeasureTime frame
CSF rhinorrheaTimepoint: Two months after surgery—

Secondary

MeasureTime frame
Not applicableTimepoint: Not applicable—

Countries

India

Contacts

Public ContactAwadhesh Kumar Jaiswal

Sanjay Gandhi Postgraduate Institute of Medical Sciences

jaiswal_dr_2002@yahoo.co.in05222495193

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026