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Ondensetron verses Dexamethasone and Ondensetron combination for nausea and vomitting-A study

Comparison of ondensetron and combination of ondensetron and dexamethasone as a prophylaxis of postoperative nausea and vomiting (PONV) in adults with laprascopic surgeries â?? A randomized non cross over trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029051
Enrollment
50
Registered
2020-11-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A will receive 4 miligrams of Ondansetron intravenous (IV): Preoperative visit will be conducted on the previous day of surgery. Detailed history and present complaints will be no

Sponsors

Nikhil Mudgalkar
Lead Sponsor
abhinov
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: The inclusion criteria of the patients were Patients of ASA grade I and II, Patients between 20 to 45 years of age ,Patients weighing between 30 to 70 kilogram

Exclusion criteria

Exclusion criteria: Patients belonging to ASA grade III and IV,Patients who are obese,Pregnant women,Patients with history of motion sickness,Patients who have received antiemetic within 24 hours of surgery,Patients on chronic steroid therapy,Patients suffering from diabetes mellitus, intestinal obstruction and hiatus hernia, renal and hepatic diseases

Design outcomes

Primary

MeasureTime frame
The number of episodes of emesis and nausea will be recordedTimepoint: every 1 hour till first 4 hour then every 4 hourly till next 24 hours

Secondary

MeasureTime frame
any side effects of the drug need for rescue antiemeticTimepoint: upto 24 hours

Countries

India

Contacts

Public ContactNikhil Mudgalkar

Prathima Institute Of Medical Sciences

drniks2000@yahoo.com08019615167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026