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To compare effect of prophylactic lignocaine and dexamethasone nebulisation on sore throat after endotracheal intubation.

Comparison of effect of prophylactic nebulisation with lignocaine and dexamethasone on post operative sore throat after endotracheal intubation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/029013
Enrollment
150
Registered
2020-11-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J069- Acute upper respiratory infection,unspecified

Interventions

Intervention1: Lignocaine: nebulisation with lignocaine 15 minutes prior to surgery. Control Intervention1: Dexamethasone: nebulisation with dexamethasone 15 minutes prior to surgery

Sponsors

GGSMCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Adult patients with equal numbers of males and females aged between 20 and 55 years. 2) Patients belonging to ASA I or II.

Exclusion criteria

Exclusion criteria: 1) Refusal of patient to give consent. 2) Known allergic to lignocaine or dexamethasone. 3) Patients belonging to ASA III or IV. 3) Anticipated difficult intubation. 4) Patients requiring >2 attempts at intubation or requiring bougie for intubation. 5) Patients on corticosteroids or any other anti inflammatory analgesic. 6) Patients undergoing head and neck surgeries. 7) Patients having renal, hepatic dysfunction or cardiovascular dysfunction. 8) Psychiatric disorders or drug abuse.

Design outcomes

Secondary

MeasureTime frame
To compare the effect of prophylactic nebulisation with lignocaine and dexamethasone on incidence and severity of post operative cough and hoarseness of voice after endotracheal intubation. Timepoint: Post operatively at 0, 6, 12, 24 hour

Primary

MeasureTime frame
To compare the effect of prophylactic nebulisation with lignocaine and dexamethasone on incidence and severity of post operative sore throat after endotracheal intubation. Timepoint: Post operatively at 0, 6, 12, 24 hour

Countries

India

Contacts

Public ContactDr Sarvjeet Kaur

G.G.S. Medical College and Hospital, Faridkot.

drsarvjeetk@gmail.com9915680508

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026