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A clinical trial to compare the effects of A-PRF and L-PRF in the treatment of intrabony periodontal defects

A-PRF in the treatment of intrabony defects as compared to L-PRF - An experimental study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/028962
Enrollment
26
Registered
2020-11-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: R50-R69- General symptoms and signs

Interventions

Intervention1: APRF: APRF has lower speed of centrifugation contains higher amounts of platelets and growth factors and possesses better mechanical properties Control Intervention1: APRF versus LPRF:

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Two and three-wall intrabony defects greater or equal than 3 mm on an intraoral periapical radiograph [IOPA]along with a probing depth (PD) of greater or equal than 5 mm after Phase 1 therapy (scaling and root planning [SRP] in an asymptomatic tooth. Age group -30-65years. Absence of caries , pulpal pathology and severe occlusal interference at selected site. Systemically healthy, non â??lactating, non-pregnant with no contraindication for periodontal surgery Patients who give consent

Exclusion criteria

Exclusion criteria: Systemic illness known to affect the outcomes of periodontal therapy; Individuals allergic to medications. Pregnant or lactating women Patients using tobacco in any form Patients with unacceptable oral hygiene (PI greater than 1.5) Patients with gingival recession, endodontic pulpal involvement ,or mobility of tooth greater than or equal to grade 2(15).

Design outcomes

Primary

MeasureTime frame
Modifications to centrifugation speed and time with the low-speed concept is expected to produce Decrease in probing pocket depth Increase in clinical attachment level. Timepoint: 1 month

Secondary

MeasureTime frame
Increase bone regeneration. Timepoint: 6 months

Countries

India

Contacts

Public ContactPrameetha George Ittycheria

Pushpagiri College of Dental Sciences

prameethageorgeittycheria@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026