Health Condition 1: P599- Neonatal jaundice, unspecified
Conditions
Interventions
Intervention1: Intermittent Phototherapy (12 hours on and 12 hours off): Intermittent phototherapy will involve keeping the neonate under phototherapy for 12 hours with interruptions for feeding and c
Sponsors
Defence Research and Development Organization
Eligibility
Inclusion criteria
Inclusion criteria: • All late preterm (>= 35 weeks) and term neonates who need phototherapy for treatment of neonatal hyperbilirubinemia as per AAP guidelines (Low and Medium risk groups) either during birth hospitalization or readmitted after discharge in the first two weeks
Exclusion criteria
Exclusion criteria: High risk group as per AAP Guidelines Onset of jaundice in the first 24 hours after birth TSB in the exchange range at enrollment Hemolytic jaundice (positive direct coombs test, evidence of hemolysis on peripheral blood smear or reticulocyte count > 6%) Any neonate admitted in NICU Major congenital malformations Direct hyperbilirubinemia (direct bilirubin > 15% of total or > 1.0 mg/dl)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary: To compare the rate of decline of bilirubin (difference between bilirubin at enrolment and at end of phototherapy divided by duration of phototherapy) between neonates treated with intermittent versus continuous phototherapy. Timepoint: At start of phototherapy, 12-hourly intervals and at end of phototherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary: To compare the duration of phototherapy, failure of phototherapy, side effects of phototherapy, duration of hospital stay, breastfeeding rates and parental satisfaction between neonates treated with intermittent versus continuous phototherapy. Timepoint: During treatment with phototherapy. Duration of hospital stay | — |
Countries
India
Contacts
Public ContactCol G Shridhar
Armed Forces Medical College
Outcome results
None listed